| Theresa A. Jones | May, 2007 |
| Psychology Department | Lab phone: 512-475-7763 |
| Seay Hall 5.248 | FAX: 512-475-7765 |
| University of Texas | Office phone: 232-1814 |
| Austin, TX 78712 | e-mail: tj@psy.utexas.edu |
Education
| Ph.D. | 1992 | University of Texas at Austin, Psychology |
| B.A. | 1987 | University of Texas at Austin, Psychology |
| 1983-1986 | University of Missouri-Columbia, Psychology |
Professional Experience
| 2008- | Professor |
| 2003-2008 |
Associate Professor |
| 2001-2003 | Assistant Professor |
| Psychology Department and Neuroscience Institute | |
| The University of Texas at Austin | |
| 1996-2001 | Assistant Professor |
| Psychology Department and Neurobiology and Behavior Program | |
| University of Washington | |
| 1993-1996 | Postdoctoral Fellow |
| Behavioral Neuroscience and Biopsychology | |
| Beckman Institute, University of Illinois | |
| Advisor: William T. Greenough | |
| 1987-1992 | Graduate Student |
| Psychology Department and Neuroscience Institute | |
| University of Texas at Austin | |
| Advisor: Timothy Schallert |
Honors and Awards
Research Funding
NIMH RO1 MH/NS64586, "Neural mechanisms of compensating for brain damage", P.I., 2002-2012
DOD NF073046 "Neural plasticity and neurorehabilitation following traumatic brain injury", TBI Concept Award (Dorothy Kozlowski, DePaul Univ., P.I.), Co-I., 2008-2010
NINDS U54 NS048126, “Cortical stimulation to enhance recovery after stroke”, Program project grant (Randy Nudo, U. Kansas, program director), PI on subproject 2: “Combination of cortical stimulation with other therapies” 2005-2009
NIH P20 RR0207700 “New Directions in Stroke Neurorehabilitation” Exploratory center grant (Tom McNeill, UCSC, program director), Co-PI with T. Schallert on subproject 3: “Influence of behavioral experience on stroke neurorehabilitation” 2004-2007
NSF IBN0347020, “Brain plasticity and division of labor: from simple to complex societies”, co-PI with S. O’Donnell, U. Washington, 2004-2008
Vertis Neuroscience Inc., Grant and Gift “Rehabilitation after stroke II”, P.I., 2001-2002
NIMH R29 FIRST, MH56361, "Behavior-mediated neural plasticity after brain damage", P.I., 1997-2002
Vertis Neuroscience Inc., "Rehabilitation after stroke", P.I., 2001
NIMH Behavioral Science Rapid Transition Award, MH55525, "Behavior, degeneration and plasticity after brain damage", P.I., 1996-1997
NRSA Postdoctoral Fellowship, 1993-1996
NIH Neurobiology Training Fellowship 1988-1991
Selected Honors
Raymond Dickson Centennial Teaching Fellow, 2006
American Psychology Association Fellow, 2006
Top 10 Great Dissertations, American Psychological Science, 2004
Faculty Development Summer Research Award, 2002
Donald B. Lindsley Award in Behavioral Neuroscience 1993
University Scholarship 1984-1986
Arts and Sciences Alumni Scholarship 1984; G. Ellsworth Huggins Scholarship 1983-1986
Publications
Peer Reviewed Publications:
Barth, T. M., Jones, T. A. and Schallert, T. (1990).
Functional subdivisions of the rat sensorimotor cortex. Behavioural Brain Research, 39,
73-95.
Schallert, T., Jones, T. A. and Lindner, M. D. (1990).
Multilevel transneuronal degeneration after brain damage:
Behavioral events and effects of anticonvulsant gamma-aminobutyric
acid-related drugs. Stroke,
21 (Suppl.III),143-146.
Jones, T. A. and Schallert, T. (1992). Overgrowth and
pruning of dendrites in adult rats recovering from neocortical
damage. Brain Research,
581, 156-160.
Jones, T. A. and Schallert, T. (1992). Subcortical
deterioration after cortical damage: Effects of diazepam and
relation to recovery of function. Behavioural Brain Research, 51,
1-13.
Schallert, T. and Jones, T. A. (1993). "Exuberant"
neuronal growth after brain damage in adult rats: The essential
role of behavioral experience. Journal
of Neural Transplantation and Plasticity, 4, 193-198.
Schallert, T., Norton, D. and Jones, T. A. (1993). A
clinically relevant unilateral rat model of Parkinsonian
akinesia. Journal of Neural
Transplantation and Plasticity, 3, 332-333.
Jones, T. A. and Schallert, T. (1994). Use-dependent
growth of pyramidal neurons after neocortical damage. Journal of Neuroscience, 14,
2140-2152.
Kozlowski, D. A., Jones, T. A. and Schallert, T. (1994).
Pruning of dendrites and restoration of function after brain
damage: Role of the NMDA receptor. Journal of Restorative Neurology and
Neuroscience, 7, 119-126.
Jones, T. A. and Greenough, W. T. (1996).
Ultrastructural evidence for increased contact between astrocytes and
synapses in rats reared in a complex environment. Neurobiology of Learning and Memory,
65, 48-56.
Jones, T. A., Hawrylak, N. and Greenough, W. T. (1996).
Rapid laminar-dependent changes in GFAP immunoreactive astrocytes in
the visual cortex of rats reared in a complex environment. Psychoneuroendocrinology, 21,
189-201.
Jones, T. A., Kleim, J. A. and Greenough, W. T. (1996).
Synaptogenesis and dendritic growth in the cortex opposite unilateral
sensorimotor cortex damage in adult rats: A quantitative electron
microscopic examination. Brain
Research, 733, 142-148.
Jones, T. A., Klintsova, A. Y., Kilman, V. L., Sirevaag, A. M. and
Greenough, W. T . (1997). Induction of multiple synapses by
experience in the visual cortex of adult rats. Neurobiology of Learning and Memory,
68, 13-20.
Jones, T. A., Hawrylak, N., Klintsova, A. Y. and Greenough, W.
T. (1998). Brain damage, behavior, rehabilitation,
recovery, and brain plasticity. Mental
Retardation and Developmental Disabilities Research Reviews, 4,
231-237.
Kleim, J. A., Swain, R. A., Armstrong, K. A., Napper, R. M. A.,
Jones, T. A. and Greenough, W. T. (1998). Selective
synaptic plasticity within the cerebellar cortex following complex
motor skill learning. Neurobiology
of Learning and Memory, 69, 274-289.
Crowder, K. M., Gunther, J. M., Jones, T. A ., Hale, B. D., Zhang,
H. Z.,
Peterson, M. R., Scheller, R. H., Chavkin, C. and Bajjalieh, S.
M. (1999).
Abnormal neurotransmission in mice lacking synaptic vesicle protein 2A
(SV2A).
Proceedings of the National Academy
of Sciences (USA), 96, 15268-15273.
Jones, T. A. (1999). Multiple synapse formation in the
motor cortex opposite unilateral sensorimotor cortex lesions in adult
rats. Journal of Comparative
Neurology, 414, 57-66.
Jones, T. A., Chu, C. J., Grande, L. A. and Gregory, A. D.
(1999). Motor skills training enhances lesion-induced structural
plasticity in the motor cortex of adult rats. Journal of Neuroscience, 19,
10153-10163.
Bury, S. D., Adkins, D. L., Ishida, J. T., Kotzer, C. M, Eichhorn,
A. C.
and Jones, T. A. (2000). Denervation facilitates neuronal
growth
in the motor cortex of rats in the presence of behavioral demand.
Neuroscience
Letters, 287, 85-88.
Bury, S. D., Eichhorn, A. C., Kotzer, C. M. and Jones, T. A.
(2000). Reactive astrocytic responses to denervation in the motor
cortex of adult rats are sensitive to manipulations of behavioral
experience. Neuropharmacology,
39, 743-755.
Chu, C. J. and Jones, T. A. (2000). Experience-dependent
structural plasticity in cortex heterotopic to focal sensorimotor
cortical damage. Experimental
Neurology, 166, 403-414.
Adkins, D. L., Bury, S. D. and Jones, T. A. (2002).
Laminar-dependent dendritic spine alterations in the motor cortex of
adult rats following callosal transection and forced forelimb use. Neurobiology of Learning and Memory,
78, 35-52.
Roitman, M. F., Na, E., Anderson, G., Jones, T. A. and Bernstein, I.
L. (2002). Induction of a salt appetite alters dendritic
morphology in nucleus accumbens and sensitizes rats to
amphetamine. Journal of
Neuroscience, 22, RC225, 1-5.
Voorhies, A. C. and Jones, T. A. (2002). The behavioral
and dendritic growth effects of focal sensorimotor cortical damage
depend on the
method of lesion induction. Behavioural
Brain Research, 133, 237-246.
Bury, S. D. and Jones, T. A. (2002). Unilateral
sensorimotor cortex lesions in adult rats facilitate motor skill
learning with the “unaffected” forelimb and training-induced dentritic
structural plasticity in the motor cortex. Journal of Neuroscience, 22,
8597-8606.
Sakata, J. T. and Jones, T. A. (2003). Synaptic mitochondrial changes in the motor cortex following unilateral cortical lesions and motor skills training in adult male rats. Neuroscience Letters, 337, 159-162.
Jones, T. A., Bury, S. D., Adkins D. L., Allred, R.P., Luke, L.
M.
and Sakata, J. T. (2003). The importance of behavioral manipulations
and
measures in rat models of brain damage and brain repair. Institute for Laboratory
Animal Research Journal. 44, 144-152.
Allred, R. P. and Jones, T. A. (2008). Maladaptive effects of learning with the less-affected forelimb after focal cortical infarcts in rats. Experimental Neurology, 210: 172-181
Kleim, J. A. and Jones, T. A. (2008). Principles of experience-dependent neural plasticity: Implications for rehabilitation after brain damage. Journal of Speech Language and Hearing Research, 51: S225-S239.
Allred, R. P. and Jones, T. A. (2008). Experience--a double edged sword for restorative neural plasticity after brain damage. Future Neurology. 3: 189-198.
Allred, R. P., Adkins, D. L., Woodlee, M. T., Husbands, L. C., Maldonado, M. A., Kane, J. R., Schallert, T. and Jones, T. A. (2008). The Vermicelli Handling Test: a simple quantitative measure of dexterous forepaw function in rats. Journal of Neuroscience Methods, 170: 229-244.
Maldonado, M. A., Allred, R. P., Felthauser, E. L. and Jones, T. A. (2008). Rehabilitative training, but not voluntary running, improves recovery of skilled reaching after unilateral ischemic lesions of the sensorimotor cortex in rats. Neurorehabilitation and Neural Repair, 22: 250-261.
Adkins, D. L., Hsu, J. E. and Jones, T. A. (2008). Motor cortical stimulation promotes synaptic plasticity and behavioral improvements after sensorimotor cortical infarcts in rats. Experimental Neurology, 212: 14-28.
Jones, T. A., Allred, R. P., Adkins, D. L., Hsu, J. E., O'Bryant, A., Maldonado, M. A. Remodeling the brain with behavioral experience after stroke. Stroke, in press.
Book Chapters and Reviews
Schallert, T., Jones, T. A., Weaver, M. S., Fulton, R. L., Shapiro,
L. E., Crippens, D. and Fulton, R. (1992). Pharmacologic
and anatomic considerations in recovery of function. In S. L.
Hanson and D. M. Tucker (Eds.), Physical
medicine and rehabilitation: State of the art reviews: Vol. 6,
Neuropsychological assessment (pp.375-393). Philadelphia:
Hanley & Belfus Inc.
Swain, R. A., Armstrong, K. E., Comery, T. A., Humphreys, A. G.,
Jones, T. A., Kleim, J. A. and Greenough, W. T. (1995).
Speculations on the fidelity of memories stored in synaptic
connections. In D. L. Schacter, J. T. Coyle, G. D. Fischbach,
M.-M. Mesulam, & L. E. Sullivan (Eds.), Memory distortion (pp.
274-297). Cambridge: Harvard University Press.
Black, J. E., Jones, T. A., Nelson, C. A. and Greenough, W. T.
(1997). Chapter 2, Neuronal plasticity and the developing
brain. In J. D. Noshpitz, N. E. Alessi, J. T. Coyle, S. I.
Harrison and S. Eth (Eds.), Handbook
of child
and adolescent psychiatry, Vol 6, Basic psychiatric treatment and
science (pp. 31-53). New York: John Wiley & Sons.
Schallert, T., Humm, J. L., Bland, S., Jones, T. A., Kolb, B.,
Aronowski, J. and Grotta, J. (2001). Activity-associated
growth factor expression and related neuronal events in recovery of
function after brain injury. In H. H. Batjer, L. R. Caplan, L.
Friberg, & W. L. Young (Eds.),
Cerebrovascular disease (pp. 410-416). Armonk, NY:
Futura Publishing Co. Inc.
Jones, T. A. and Greenough, W. T. (2002). Chapter 19,
Behavioral experience-dependent plasticity of glial-neuronal
interactions. In A.
Volterra, P. Magistretti, & P. G. Haydon (Eds.), Glia in synaptic transmission
(pp. 248-265). Oxford University Press.
Jones, T. A. (in editorial review) Cortical reorganization due to experience, Chapter 3: Experience dependent changes in non-humans. In S. A. Raskin (Ed.), Neuroplasticity and Neurorehabilitation. New York: Guilford Publications, Inc.
Journal Cover Illustrations:
Jones, T. A. and Greenough, W. T., (1996). Schematic of astrocytic coverage of synaptic elements, Neurobiology of Learning and Memory, 65.
Jones, T. A., Kleim, J. A. and Greenough, W. T. (1996). Electron micrograph of layer V of the rat motor cortex, Brain Research, 733.
Adkins, D. L., Bury, S. D. and Jones, T. A. (2002). Layer II/III and V pyramidal neurons in the forelimb representation region of the rat motor cortex. Neurobiology of Learning and Memory, 78.
Conference Proceedings Abstracts, Last 3 years (out of 57 total):
Allred R. P., Parikh T. J. and Jones, T. A. (2005). Effects of unilateral and bilateral skilled reach training on impaired forelimb function following unilateral sensorimotor cortex damage in rats. Society for Neuroscience Abstracts, 31, 333.13
O'Bryant, A., Bernier, B. and Jones, T.A. (2005). Bilateral effects of unilateral ischemic sensorimotor cortex lesions on skilled reaching in rats. Society for Neuroscience Abstracts, 31, 333.14
Hsu, J. E. and Jones, T. A. (2005). Enhancement of motor skill learning in the "less affected" forelimb after unilateral infarcts of the sensorimotor cortex in rats: Influence of lesion size and ipsilesional impairments. Society for Neuroscience Abstracts, 31, 333.15.
Adkins, D. L., Hsu, J. E. and Jones, T. A. (2005). The efficacy of cortical electrical stimulation combined with motor rehabilitation after cortical ischemia depends on the magnitude of impairment. Society for Neuroscience Abstracts, 31, 548.9.
Maldonado, M. A., Felthauser, E. L. and Jones, T. A. (2005). Effects of exercise on motor rehabilitation in aged rats after unilateral focal ischemic lesions of the sensorimotor cortex. Society for Neuroscience Abstracts, 31, 997.17.
Maldonado, M. A., Allred, R. P., Hsu, J. E. and Jones, T. A. (2006). The contribution of the “intact” hemisphere to recovery of skilled reaching after unilateral ischemic sensorimotor cortex lesions in rats. Society for Neuroscience Abstracts, 32, 161.8.
O’Bryant, A., Sitko, A., Houke, B. and Jones, T. A. (2006). The effects of cortical electrical stimulation and forced forelimb use on the recovery of skilled reaching after unilateral ischemic sensorimotor cortex lesions in rats. Society for Neuroscience Abstracts, 32, 161.6.
Hsu, J. E., Adkins, D. L., and Jones, T. A. (2006) Cortical electrical stimulation during motor rehabilitation increases synaptic density in the peri-lesion cortex after unilateral cortical ischemia in rats. Society for Neuroscience Abstracts, 32, 161.7.
Husbands, L. C., Parikh, T. J., Hsu, J. E. and Jones, T. A. (2006) Endothelin-1 induced occlusion of the middle cerebral artery produces persistent forelimb deficits and bilateral dendritic structural plasticity in layers II/III and V of sensorimotor cortex in rats. Society for Neuroscience Abstracts, 32, 582.4.
Allred, R. P. and Jones, T.A. (2006) Training the "good" forelimb after unilateral sensorimotor cortex lesions worsens function of the impaired forelimb and alters peri-lesion neuroplasticity. Society for Neuroscience Abstracts, 32, 161.9.
O'Bryant, A., Sitko, A., Jones, T.A. (2007) Cortical stimulation results in a chronic enhancement in behavioral function after cortical infarcts in rats. Stroke, 2007 (peer reviewed)
Hsu, J. E., Donlan, N. A., Jones, T. A. (2007) Protein synthesis inhibition in the perilesion cortex disrupts functional recovery and structural plasticity induced by rehabilitative training after unilateral cortical infarct in rats. Society for Neuroscience Abstracts, 33, in press.
O'Bryant, A., Sitko, A., and Jones, T.A. (2007) Cortical stimulation results in a chronic enhancement in behavioral function after cortical infarcts in rats. Stroke, 38, 520. (peer reviewed)
Markam, R. G, Tennant, K. A. and Jones, T. A. (2007) Training the less-affected forelimb after SMC unilateral infarct alters motor cortical representations among the two hemispheres Society for Neuroscience Abstracts, 33, 82.17.
O'Bryant, A. O. and Jones, T. A. (2007) Within-strain differences in skilled reaching behavior in adult long-evans rats. Society for Neuroscience Abstracts, 33, 206.6
Jones, T. A., Sitko, A. A. and Allred, R. P. (2007) Functional variability and motor cortical dendritic plasticity in C57BL/6 mice learning a skilled reaching task. Society for Neuroscience Abstracts, 33, 206.7.
Maldonado, M. A., High, D. P., Hays, S. A., Allred, R. P. and Jones, T. A. (2007) The effects of every other day fasting on behavioral recovery from focal cortical ischemia in rats. Society for Neuroscience Abstracts, 33, 899.3.
Allred, R., Adkins, D. L., Maldonado, M. A., Husbands, L. C., Markham, R. G. and Jones, T. A. (2007) The pasta handling test: a simple quantitative measure of forepaw dysfunction in rats. Society for Neuroscience Abstracts, 33, 899.5.
Hsu, J. E., Donlan, N. A. and Jones, T. A. (2007) Protein synthesis inhibition in the perilesion cortex disrupts functional recovery and structural plasticity induced by rehabilitative training after unilateral cortical infarct in rats. Society for Neuroscience Abstracts, 33, 899.15.
Symposia and Conferences
Society for Neuroscience, 1987-2007
National Neurotrauma Society Meeting, 1997, 2000, 2004, 2007
Winter Conference on Neural Plasticity, 2002, 2006, 2008
International Stroke Conference, 2007
Winter Conference for Brain Research, 1994, 1998, 1999, 2003
International Symposium on Chronic Recovery from Stroke, 2002
11th Nordic Meeting on Cerebrovascular Diseases, 2001
American Stroke Association, 2001
Neural Plasticity, 2000
Chicago Society for Neuroscience, 1995
Workshop in Practical Applications in Stereology, 1995
First International Conference on Glial Contributions to Behavior, 1995
Basics of Molecular Biology for Neurobiologists, 1995
First American Course in Stereology, 1990
Neural Regeneration Symposium, 1989
COMMITTEES AND SERVICE
APA Committee on Animal Research and Ethics (CARE) 2006-
Stroke Program Review Group, National Institute of Neurological
Disorders and Stroke, 2006
NIH study section, CND/ANIE, Temporary
reviewer, 2004-2006, Regular Member 2006-2010
NIH study section, Brain Disorders and Clinical Neuroscience, Temporary
reviewer, June 2006
American Heart Association Texas Affiliate's Research Allocations &
Advisory Committee, 2006-
American Heart Association Western Review Consortium, Peer review
member 2005-2009
National Neurotrauma Society Program Committee, 2005-2006
National Neurotrauma Society Abstract Review Committee, 2006
Society for Neuroscience Central Texas Chapter, Secretary 2004-2006
Stroke Program Review Group, National Institute of Neurological
Disorders and Stroke, 2001
Co-Chair, Symposium on Behaviour-Induced Neural Events after Brain
Injury, Internet World Congress on Biomedical Sciences 1998
Professional Organizations
Society for Neuroscience
American Psychological Association, Division 6
American Psychological Society
American Heart/Stroke Association
National Neurotrauma Society
Faculty for Undergraduate Neuroscience