I
study how behavioral experiences influence functional
recovery after unilateral stroke-like injuries of the sensorimotor
cortex in rats. I recently discovered that training the
"good" forelimb of rats after these injuries worsens function in the
impaired limb. My dissertation is focused on understanding the
characteristics and neural basis of this effect.
J. Edward Hsu
Graduate Student
My dissertation research is focused on understanding the
neural mechanisms of motor rehabilitation after stroke, as modeled in
rats with unilateral cortical ischemia. I have recently
discovered that rehabilitative reach training drives synaptogenesis and
other neuroplastic changes in remaining cortex. In
additional research, I am attempting to determine the necessity of
these changes for functional recovery.
Soo Young
Kim
Graduate Student
I am interested in glia-neuronal interactions in
synaptic plasticity and recovery from brain damage. My current
research is focused on age-related differences in the remodeling of
neocortical astrocytes and synapses after brain damage.
Monica A.
Maldonado
Graduate Student
One of my primary interests is how cell proliferation,
including neurogenesis, contributes to functional recovery after brain
damage in adult animals. My dissertation research is focused on
the potential of motor rehabilitative training to drive neocortical
gliagenesis and neurogenesis.
Rebecca
Markham
Postdoctoral Fellow
My current research is focused on how behavioral
experiences influence the reorganization of movement representations in
the primary motor cortex of rats after cortical ischemia.
Prior to joining the Jones' laboratory, I studied the role of sensory
experience in brain development. I hope in the future to combine
these lines of research in a new model system of pediatric stroke for
investigation of experience-dependent reorganization of developing
brains.
Amber
O'Bryant
Graduate Student
My dissertation research focus is the use of a novel
treatment approach, motor cortical stimulation (CS), for stroke-induced
functional impairments. I have recently discovered that combining
CS with motor rehabilitative training results in functional
improvements that persist for at least 9-10 months after the end
of treatment compared to rats receiving rehabilitative training
alone. My current research is focused on understanding the
effective timing of this treatment after stroke-like injuries in rat
and its influence on neural activity and plasticity in residual
sensorimotor cortex.
Kelly Tennant
Graduate Student I have broad
interests in neural plasticity after brain damage, having just joined
the laboratory in January, 2007. My current research is focused
on developing a new mouse model suitable for in vivo investigations of
neocortical plasticity linked to motor learning and recovery from
cortical infarct.