Collaborations
& funding
Grant: P01 NS 19608-19 (NIH)
Period: August 2003 – July 2008
PI: Michael Zigmond
(
Dr. Schallert’s role: Director of Behavioral Core
Title: Early
detection, compensation and neuroprotection in Parkinson’s disease
This project's focus is on use-dependent neural events associated
with exercise and other forms of motor enrichment, and using motor enrichment
to slow or halt progressive degeneration of dopamine neurons after exposure to
neurotoxins.
Grant: P01 NS 24707 (NIH)
Period: July 2001 – July 2006
PI: Marian Murray (
Dr. Schallert’s role: Co-Director
of Behavioral Core
Title: Recovery of function after spinal cord damage
This study examines the behavioral and anatomical effects of
transplantation of genetically engineered fibroblasts delivering the
neurotrophic factor BDNF after unilateral spinal cord injury, and the
interaction of BDNF and motor rehabilitation.
Grant: P01 NS 42345
(NIH)
Period: October 2003 –
September 2008
PI: Michael Chopp (
Dr. Schallert’s role: Director of
Behavioral Core and Co-PI, Project 3
Title: Treatment of stroke and traumatic brain
injury with marrow stromal cells
This study examines the use of marrow stromal cells in the
treatment of stroke and traumatic brain injury
Grant: UTA 04-078
(DARPA)
Period: July 2003 –
June 2007
PI: Paul Garris (
Dr. Schallert’s role: Co-PI for the
subcontract
Title: Phasic
dopaminergic signaling and the pre-symptomatic phase of Parkinson’s disease.
This study will attempt to understand the role of phasic dopamine signaling in mechanisms of plasticity and functional
outcome after partial degeneration of dopamine terminals.
Grant: P20 RR 20700 (NIH)
Period: September 2004 – August 2007
PI: Tom McNeill (
Dr. Schallert’s
role:
Co-PI, Study 3
Title: New Directions in Stroke Neurorehabilitation
The studies proposed use an interdisciplinary
approach to examine the synergy between neural plasticity and treatment
strategies that promote the recovery of upper limb motor function after
stroke-induced brain injury. The long-term goals of our study are: 1) to broaden
our understanding of the key factors that modulate neuroplasticity and the
recovery of function after brain injury, 2) build a foundation of
interdisciplinary scientific knowledge that can be used in the development of
innovative and more effective therapeutic
interventions to enhance the health and independence of persons with
post-stroke disabilities; and 3) provide an
interdisciplinary training opportunity for (basic science and clinical)
graduate and post-doctoral students to develop as independent research
scientists equipped to work both within and across scientific disciplines
Grant: HD-02-023 (NIH)
Period: September 2003 – August 2008
PI: Jack Parent (
Dr. Schallert’s role: Co-PI/Consultant
Title: Pharmacological approaches
to enhance neuromodulation in rehabilitation
The goal of this research is to determine whether
pharmacological (growth/differentiation factors or astrocyte-derived cues)
alone, or in combination with motor enrichment, will stimulate neurogenesis and
improve functional recovery after stroke (MCAo) in the adult rat.